Year : 2015  |  Volume : 22  |  Issue : 1  |  Page : 158-159

A case of trientine overdose

Digestive Diseases Centre, Brighton and Sussex University Hospitals NHS Trust, Brighton, United Kingdom

Correspondence Address:
Ahmed Hashim
Royal Sussex County Hospital, Brighton and Sussex University Hospitals NHS Trust, Eastern Road, Brighton
United Kingdom
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DOI: 10.4103/0971-6580.172262

PMID: 26862278

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Wilson disease is a rare genetic hepatic and neurological disorder of copper accumulation. Trientine is usually used as a second line in the management of patients with this condition. We present a case of a large overdose of Trientine (60 g) resulting in self-limiting dizziness and vomiting with no further clinical sequelae or significant biochemical abnormalities. This case shows that Trientine has a good safety profile and hence could be used as a first line treatment in patients with Wilson's disease who suffer from psychiatric complications and who might be at risk of self-harm.

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